Mon Jan 7, 2013 8:39pm EST
SEOUL Jan 8 (Reuters) - South Korea's main KOSPI share index was down 0.2 percent at 2,006.89 points at 0106 GMT. The index opened down 0.4 percent.
VGX International shot up 11.9 percent after its U.S-based parent company, Inovio Pharmaceuticals Inc, entered into a follow-on agreement with the Bill Gates-backed PATH's malaria vaccine initiative to develop an effective malaria vaccine.
Inovio Pharmaceuticals gained 17 percent on Monday.
Keystone Global plunged 7.1 percent after it announced on Monday that a 67.9 billion won ($63.82 million) order it secured in 2008 for a wind power plant was cancelled in 2011.
The contract is worth 67.5 percent of 2011 sales.
The regulation authority, Korea Exchange, issued a warning to the firm for its belated notice. ($1 = 1064.0000 Korean won) (Reporting by Somang Yang; Editing by Stephen Coates and Anand Basu)
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